

Liposomal Methylfolate Liquid
Our Liposomal Methylfolate is a premium supplement providing 5-Methyltetrahydrofolate (5-MTHF), a readily usable form of folate, encapsulated in non-GMO sunflower phospholipids designed to replicate the phospholipid assemblies and bilayer architecture found in cell membranes.
Ingredient Facts
Folate Contributes to:
- Maternal tissue growth during pregnancy
- Normal amino acid synthesis
- Normal blood formation
- Normal homocysteine metabolism
- Normal psychological function
- The normal function of the immune system
- The reduction of tiredness and fatigue
- Plays a role in the process of cell division
Dosage
Shake before use. Take 1 ml per day, or as professionally directed. Best taken when chilled. Do not exceed the stated recommended daily dose.
Store in a cool, dry place below 20°C. Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle. Pregnant or breastfeeding women, or those under medical supervision, should consult a doctor before use. Keep out of reach of young children. Keep tightly sealed and protected from light and heat.
Allergy Info: Gluten Free, Lactose Free, Paraben Free
Ingredients
Formulated with:
- Folate (as 5-Methyltetrahydrofolate) – 500 µg
- Phospholipids (Non-GMO Sunflower)
- Glycerol
- Potassium Sorbate (preservative)
- Vitamin E (as Mixed Tocopherol)
- Citric Acid (as pH regulator)
Advisory
Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle.
Do not exceed the stated recommended daily dose.
Keep out of the reach of young children.
Quality Standards
Our Liposomal Methylfolate Liquid is manufactured in the UK to GMP standards by GM Priority Pharma. Each batch undergoes independent third-party testing for purity, potency, and safety. 5-Methyltetrahydrofolate (5-MTHF) is encapsulated in microscopic spheres made from non-GMO sunflower phospholipid bilayers, the same structural motif that forms phospholipid cell membranes.
Liposomal formulations containing other B vitamins have been characterised in human studies that tracked nutrient levels in blood over time after supplementation, using pharmacokinetic metrics such as plasma concentrations and time–concentration curves. In vitro digestion and stability studies have evaluated similar liposomal methylfolate formulations, demonstrating substantial 5-MTHF retention under various stress conditions and protection of the vitamin during simulated digestion. The formulation is non-GMO, recyclable, and packaged in UV-protected glass bottles to help protect product stability and integrity over its shelf life.
Why Liposomal Methylfolate
Our liposomal Methylfolate uses non-GMO sunflower-derived phospholipids for encapsulation, forming membrane-like spheres that surround the water-soluble folate form. In our Liposomal Delivery, methylfolate is carried within microscopic sunflower-derived phospholipid bilayers, the same structural motif that forms phospholipid cell membranes. Instead of leaving methylfolate as a simple dissolved ingredient, this approach presents methylfolate within a liposomal matrix of phospholipids and folate, similar to the liposomal systems investigated in the
scientific literature.
Liposomes are dynamic phospholipid bilayers built from the same general type of phospholipid assemblies and bilayer architecture found in cell membranes. Both are dynamic lipid structures with fluid behaviour and the ability to curve, bud, and reorganise. In cell biology, membranes routinely exchange vesicles with the same bilayer structure during exocytosis, endocytosis, and vesicle trafficking. Liposomal systems have been the subject of numerous studies as delivery vehicles for supplement ingredients.
Liposomal formulations containing other B vitamins have been characterised in human studies that tracked nutrient levels in blood over time after supplementation, using pharmacokinetic metrics such as plasma concentrations and time–concentration curves. In vitro digestion and stability studies have evaluated liposomal methylfolate formulations, demonstrating substantial 5-MTHF retention under various stress conditions and protection of the vitamin during simulated digestion. Taken together, this makes our Liposomal Delivery Technology a premium, liquid-friendly format for modern methylfolate supplementation.
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Liposomal Encapsulation
In traditional supplements, large amounts of the active ingredients do not get absorbed. They are damaged, and destroyed by stomach acids, and intestinal enzymes. Whereas, liposomal supplements are wrapped in a protective bubble of healthy fat. This helps in:
Protection: Protect the nutrient from stomach acid and enzymes.
Absorption: Assimilate it into the bloodstream more easily.
Bio-availability: Deliver higher amounts to the cells where they’re needed.
"Within two weeks, my focus and energy noticeably improved. It’s gentle but powerful."
Anne, 37
"My doctor recommended switching from folic acid to methylfolate. The difference was immediate in energy and clarity."
Hannah, 42
"After six months of consistent use, my blood tests show healthy folate and homocysteine levels. Highly recommend."
Clare, 47
Need help?
Frequently Asked Questions
Methylfolate(5-MTHF) is the active form of folate that your body can use immediately, bypassing genetic limitations in folic-acid conversion.
Many users experience improved energy and mood within 2–4 weeks, with deeper methylation and cardiovascular benefits developing over several months. Individual results may vary.
Yes, in fact it’s ideal to pair with a B-complex to provide complete methylation and red-blood-cell support.
Yes. The formula is 100% plant-based and allergen-free.
At present, we ship exclusively within the United Kingdom.
Orders are typically delivered within 5–7 working days, depending on your location in the UK.
Scientific Footnotes
Scaglione F, Pirovano O. Comparative bioavailability of 5-methyltetrahydrofolate and folic acid. Arzneimittelforschung. 2013.
Pietrzik K et al. 5-Methyltetrahydrofolate: biological significance and clinical use. Clin Drug Investig. 2010.
Bailey SW, Ayling JE. The extremely slow and variable activity of dihydrofolate reductase in human liver: implications for high folic acid intake. PNAS. 2009.
