When Dr Francesco Lo Monaco, a world-renowned cardiologist, met his wife Audrey Elena Ottaviani, both his life and his practice were redefined. Her curiosity about healthy ageing and holistic approach pushed him beyond conventional medicine, inspiring them to blend rigorous clinical science with functional medicine. Together they developed evidence‑grounded longevity supplements and integrated nutrition, sleep, stress management and targeted supplements into personalised treatment plans. Their partnership became a model of compassionate, cross‑disciplinary care, combining acute, evidence‑based medicine with preventive, life-centred strategies, to help people live longer, healthier lives.