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Harley Street’s leading health optimisation clinic, where medical precision meets modern wellness.

Support your health and wellbeing through advanced nutrition and lifestyle support.

Clinical Excellence, Global Recognition

The National Longevity Clinic is the vision of Dr Francesco Lo Monaco, an award-winning cardiologist whose career bridges rigorous science and compassionate care. Twice honoured at the European Awards in Medicine (2022 & 2024) and named Fluxx Global Cardiologist of the Year 2025, Dr. Lo Monaco has earned over 500 five-star reviews and recognition among the top 10% of clinicians in London.

Yet the story goes deeper than accolades. His work is driven by a belief that medicine must restore vitality, not merely manage symptoms. This philosophy is shared by his co-founder and wife, Audrey Elena Ottaviani-Lo Monaco, a certified nutritional practitioner and expert in functional medicine. Together, they built a clinic focused on blending precise diagnostics, evidence-based protocols, and profoundly personal care to help each person feel more informed and supported on their wellness journey

Our Personalised Approach to Longevity

The Longevity Method

A seamless collaboration between doctors, nutritionists, and wellness specialists ensures every plan is medically grounded and uniquely yours.

1. Initial Consult

An in-depth consultation where we explore your concerns, symptoms, medical history, and health goals.

2. Assess

Comprehensive diagnostic testing across 250+ biomarkers, genetics, and biological age.

3. Optimise

Personalised medical and supplement protocols to rebalance, strengthen, and restore.

4. Sustain

Ongoing concierge monitoring and lifestyle support to maintain vitality and resilience.

Your Personalised Path to Health Optimisation

Experience a structured yet flexible programme blending diagnostics, therapies, and supplement protocols. Our Longevity Concierge packages are available as:

Begin your renewal

ORIGIN

Origin is designed as a precise, restorative immersion that reconnects you with your biological baseline. In just a weekend, it lays the foundation for improved vitality through targeted diagnostics, focused therapies, and personalised interventions.

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Rise to your higher potential

ASCEND

Ascend guides you through a month of structured, personalised interventions that elevate metabolic function, hormonal balance, and energy systems. Each week builds progressively, helping your body shift into a higher state of wellbeing.

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Reach your peak

ZENITH

Zenith is the pinnacle of personalised longevity, combining advanced diagnostics, continuous optimisation, medical supervision, and layered therapeutic strategies. It is a transformative three-month journey that reshapes your biology toward lasting vitality and long-term healthspan.

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The most thorough and reassuring health assessment I’ve ever experienced.

Client, London

"My energy, focus, and sleep have transformed in just weeks. They deliver what others promise.”

CEO, London

Blog posts

Liposomal Supplements: The New Generation of Medicine

Liposomal Supplements: The New Generation of Medicine

Liposomal supplements are redefining how we absorb vitamins, minerals, and bioactive compounds. Built on pharmaceutical-grade liposome technology, these microscopic lipid spheres shield nutrients f...

Read more